Sphere is a very cool puzzle which challenges you to escape from a locked room, using only what you find in the room. Click on a part of the room to inspect closer. Click on an object to use it or pick it up. Once an object is in your possession, it appears in the sidebar. Then, you can click on the magnifier to get a closer look. While you are inspecting an object, try clicking on it, or clicking on it with other objects.
You can solve this puzzle on your own. Just be aware that clicking is very precise, and there are a lot more areas to inspect than may be apparent at first.
Don't worry about getting into a state where you can't solve the puzzle. That doesn't seem to be an issue with this game. So, you don't need to restart in order to see if that key works in a different drawer as well. It doesn't.
If you get stuck, step away from the game and come back in a little while. Time to solve is maybe an hour or two. Maybe, less, if you are clever. :)